Seismic retrofit of reinforced concrete frames by direct loss-based design

This paper introduces a procedure for the retrofit design of reinforced concrete (RC) frame buildings to achieve the desired target level of earthquake-induced loss for a given seismic hazard profile. The methodology is "direct" because the loss target is specified in the first step of the procedure, and, in principle, no design iterations are required. The target loss level is defined based on designer/client preferences and/or external constraints (e.g., foundation capacity). The proposed procedure relies on a simplified loss assessment enabled by a surrogate model defining the probability distribution of the seismic deformation demands of single degree of freedom (SDoF) systems given different ground-motion intensity levels. Combined with a hazard curve and a building-level damage-to-loss model, such a surrogate model is used to map candidate SDoF force-displacement curves to their earthquake-induced loss by assuming a given retrofit strategy. In this case, the considered retrofit strategy involves changing the frame's local hierarchy of strength to ensure a global plastic structure mechanism. Under such assumptions, a designer can select a design force-displacement curve among those that comply with the chosen loss target. The detailing of the retrofitted frame is carried out according to the direct displacement-based design principles and the Simplified Lateral Mechanism Analysis (SLaMA). The procedure is applied to an under-designed RC frame building retrofitted with concrete jacketing. A benchmark loss estimate is calculated using non-linear time-history analyses for loss assessment purposes. The proposed procedure shows satisfactory compliance with the benchmark loss, emphasising the procedure's effectiveness in practice

Gaussian process regression-based surrogate modelling for direct loss-based seismic design of low-rise base-isolated structures

Seismic base isolation has gained popularity in the last decades. As a result, many structures are now equipped with base isolation systems to offer enhanced seismic performance and meet the needs of risk-aware stakeholders. However, a robust performance-based seismic design of these types of structures is generally not carried out due to the iterative nature of common design approaches and the time/computational resources required for such iterations, which are incompatible with the preliminary design phase. Indeed, seismic risk/loss is often just assessed at the end of the design process as a final verification step. This paper offers an overview of a simplified methodology for the seismic design of low-rise structures equipped with a base isolation system to achieve a predefined level of earthquake-induced economic loss while complying with a predefined minimum level of structural reliability. The main advantage of the proposed methodology is that it requires no design iterations. The procedure is enabled by Gaussian-process-regression-based surrogate probabilistic seismic demand modelling of equivalent single degree of freedom systems (i.e., the probability distribution of peak horizontal displacements and accelerations on top of the isolation layer conditional on different ground-motion intensity levels). Combined with simplified loss models for the base isolation system and the structural and non-structural components of the superstructure, this approach allows mapping a range of structural configurations to their resulting seismic loss. A designer can then select one of the identified combinations of the strength of the superstructure and properties of the isolation system conforming with the loss target, and reliability requirements, and consequently detail the superstructure and isolation system accordingly. This paper introduces the implemented surrogate probabilistic seismic demand models and provides an overview of a tentative Direct Loss-based Design procedure for low-rise base-isolated structures

MERRA-2: File Specification

The second Modern-Era Retrospective analysis for Research and Applications (MERRA-2) is a NASA atmospheric reanalysis that begins in 1980. It replaces the original MERRA reanalysis (Rienecker et al., 2011) using an upgraded version of the Goddard Earth Observing System Model, Version 5 (GEOS-5) data assimilation system. The file collections for MERRA-2 are described in detail in this document, including some important changes from those of the MERRA dataset (Lucchesi, 2012)

Propulsion in a viscoelastic fluid

Flagella beating in complex fluids are significantly influenced by viscoelastic stresses. Relevant examples include the ciliary transport of respiratory airway mucus and the motion of spermatozoa in the mucus-filled female reproductive tract. We consider the simplest model of such propulsion and transport in a complex fluid, a waving sheet of small amplitude free to move in a polymeric fluid with a single relaxation time. We show that, compared to self-propulsion in a Newtonian fluid occurring at a velocity U_N, the sheet swims (or transports fluid) with velocity U / U_N = [1+De^2 (eta_s)/(eta) ]/[1+De^2], where eta_s is the viscosity of the Newtonian solvent, eta is the zero-shear-rate viscosity of the polymeric fluid, and De is the Deborah number for the wave motion, product of the wave frequency by the fluid relaxation time. Similar expressions are derived for the rate of work of the sheet and the mechanical efficiency of the motion. These results are shown to be independent of the particular nonlinear constitutive equations chosen for the fluid, and are valid for both waves of tangential and normal motion. The generalization to more than one relaxation time is also provided. In stark contrast with the Newtonian case, these calculations suggest that transport and locomotion in a non-Newtonian fluid can be conveniently tuned without having to modify the waving gait of the sheet but instead by passively modulating the material properties of the liquid.Comment: 21 pages, 1 figur

A search for water maser emission toward obscured post-AGB star and planetary nebula candidates

Water maser emission at 22 GHz is a useful probe to study the transition between the nearly spherical mass-loss in the AGB to a collimated one in the post-AGB phase. In their turn, collimated jets in the post-AGB phase could determine the shape of planetary nebulae (PNe) once photoionization starts. We intend to find new cases of post-AGB stars and PNe with water maser emission, including water fountains or water-maser-emitting PNe. We observed water maser emission in a sample of 133 objects, with a significant fraction being post-AGB and young PN candidate sources with strong obscuration. We detected this emission in 15 of them, of which seven are reported here for the first time. We identified three water fountain candidates: IRAS 17291-2147, with a total velocity spread of ~96 km/s in its water maser components and two sources (IRAS 17021-3109 and IRAS 17348-2906) that show water maser emission outside the velocity range covered by OH masers. We have also identified IRAS 17393-2727 as a possible new water-maser-emitting PN. The detection rate is higher in obscured objects (14%) than in those with optical counterparts (7%), consistent with previous results. Water maser emission seems to be common in objects that are bipolar in the near-IR (43% detection rate). The water maser spectra of water fountain candidates like IRAS 17291-2147 show significantly less maser components than others (e.g., IRAS 18113-2503). We speculate that most post-AGBs may show water maser emission with wide enough velocity spread (> 100 km/s) when observed with enough sensitivity and/or for long enough periods of time. Therefore, it may be necessary to single out a special group of "water fountains", probably defined by their high maser luminosities. We also suggest that the presence of both water and OH masers in a PN is a better tracer of its youth, rather than the presence of just one of these species.Comment: To be published in Astronomy & Astrophysics. 16 pages, 1 figure (spanning 5 pages). This version includes some minor language corrections and fixes some errors in Table

Cosmological Inhomogeneities with Bose-Einstein Condensate Dark Matter

We consider the growth of cosmological perturbations to the energy density of dark matter during matter domination when dark matter is a scalar field that has undergone Bose-Einstein condensation. We study these inhomogeneities within the framework of both Newtonian gravity, where the calculation and results are more transparent, and General Relativity. The direction we take is to derive analytical expressions, which can be obtained in the small pressure limit. Throughout we compare our results to those of the standard cosmology, where dark matter is assumed pressureless, using our analytical expressions to showcase precise differences. We find, compared to the standard cosmology, that Bose-Einstein condensate dark matter leads to a scale factor, gravitational potential and density contrast that increase at faster rates.Comment: 17 pages, 2 figures; typos corrected, references adde

Mindfulness meditation targets transdiagnostic symptoms implicated in stress-related disorders: Understanding relationships between changes in mindfulness, sleep quality, and physical symptoms

Mindfulness-Based Stress Reduction (MBSR) is an 8-week meditation program known to improve anxiety, depression, and psychological well-being. Other health-related effects, such as sleep quality, are less well established, as are the psychological processes associated with therapeutic change. This prospective, observational study (n=213) aimed to determine whether perseverative cognition, indicated by rumination and intrusive thoughts, and emotion regulation, measured by avoidance, thought suppression, emotion suppression, and cognitive reappraisal, partly accounted for the hypothesized relationship between changes in mindfulness and two health-related outcomes: sleep quality and stress-related physical symptoms. As expected, increased mindfulness following the MBSR program was directly correlated with decreased sleep disturbance (r=-0.21, p=0.004) and decreased stress-related physical symptoms (r=-0.38, p<0.001). Partial correlations revealed that pre-post changes in rumination, unwanted intrusive thoughts, thought suppression, experiential avoidance, emotion suppression, and cognitive reappraisal each uniquely accounted for up to 32% of the correlation between the change in mindfulness and change in sleep disturbance and up to 30% of the correlation between the change in mindfulness and change in stress-related physical symptoms. Results suggest that the stress-reducing effects of MBSR are due, in part, to improvements in perseverative cognition and emotion regulation, two “transdiagnostic” mental processes that cut across stress-related disorders

A method to localize gamma-ray bursts using POLAR

The hard X-ray polarimeter POLAR aims to measure the linear polarization of the 50-500 keV photons arriving from the prompt emission of gamma-ray bursts (GRBs). The position in the sky of the detected GRBs is needed to determine their level of polarization. We present here a method by which, despite of the polarimeter incapability of taking images, GRBs can be roughly localized using POLAR alone. For this purpose scalers are attached to the output of the 25 multi-anode photomultipliers (MAPMs) that collect the light from the POLAR scintillator target. Each scaler measures how many GRB photons produce at least one energy deposition above 50 keV in the corresponding MAPM. Simulations show that the relative outputs of the 25 scalers depend on the GRB position. A database of very strong GRBs simulated at 10201 positions has been produced. When a GRB is detected, its location is calculated searching the minimum of the chi2 obtained in the comparison between the measured scaler pattern and the database. This GRB localization technique brings enough accuracy so that the error transmitted to the 100% modulation factor is kept below 10% for GRBs with fluence Ftot \geq 10^(-5) erg cm^(-2) . The POLAR localization capability will be useful for those cases where no other instruments are simultaneously observing the same field of view.Comment: 13 pages, 10 figure

Hemoglobin concentrations and RBC transfusion thresholds in patients with acute brain injury: an international survey.

The optimal hemoglobin (Hb) threshold at which to initiate red blood cell (RBC) transfusion in patients with acute brain injury is unknown. The aim of this survey was to investigate RBC transfusion practices used with these patients. We conducted a web-based survey within various societies of critical care medicine for intensive care unit (ICU) physicians who currently manage patients with primary acute brain injury. A total of 868 responses were obtained from around the world, half of which (n = 485) were from European centers; 204 (24%) respondents had a specific certificate in neurocritical care, and most were specialists in anesthesiology or intensive care and had less than 15 years of practice experience. Four hundred sixty-six respondents (54%) said they used an Hb threshold of 7-8 g/dl to initiate RBC transfusion after acute brain injury, although half of these respondents used a different threshold (closer to 9 g/dl) in patients with traumatic brain injury, subarachnoid hemorrhage, or ischemic stroke. Systemic and cerebral factors were reported as influencing the need for higher Hb thresholds. Most respondents agreed that a randomized clinical trial was needed to compare two different Hb thresholds for RBC transfusion, particularly in patients with traumatic brain injury, subarachnoid hemorrhage, and ischemic stroke. The Hb threshold used for RBC transfusion after acute brain injury was less than 8 g/dl in half of the ICU clinicians who responded to our survey. However, more than 50% of these physicians used higher Hb thresholds in certain conditions

Air change rates and infection risk in school environments: Monitoring naturally ventilated classrooms in a northern Italian urban context

The importance of building ventilation in avoiding long-distance airborne transmission has been highlighted with the advent of the COVID-19 pandemics. Among others, school environments, in particular classrooms, present criticalities in the implementation of ventilation strategies and their impact on indoor air quality and risk of contagion. In this work, three naturally ventilated school buildings located in northern Italy have undergone monitoring at the end of the heating season. Environmental parameters, such as CO2 concentration and indoor/outdoor air temperature, have been recorded together with the window opening configurations to develop a two-fold analysis: i) the estimation of real air change rates through the transient mass balance equation method, and ii) the individual infection risk via the Wells-Riley equation. A strong statistical correlation has been found between the air change rates and the windows opening configuration by means of a window-to-volume ratio between the total opening area and the volume of the classroom, which has been used to estimate the individual infection risk. Results show that the European Standard recommendation for air renewal could be achieved by a window opening area of at least 1.5 m2, in the most prevailing Italian classrooms. Furthermore, scenarios in which the infector agent is a teacher show higher individual infection risk than those in which the infector is a student. In addition, the outcomes serve school staff as a reference to ensure adequate ventilation in classrooms and keep the risk of infection under control based on the number of the students and the volume of the classroom